Status:

COMPLETED

Identification of Novel Circadian Biomarkers

Lead Sponsor:

Northwestern University

Conditions:

Circadian Rhythm Disorders

Eligibility:

All Genders

18-60 years

Brief Summary

Circadian clocks are not only found in discrete areas of the brain, but are found in virtually every organ in our bodies, including the heart, lungs and immune system. Disruptions in circadian clocks,...

Detailed Description

Circadian clocks are not only found in discrete areas of the brain, but are found in virtually every organ in our bodies, including the heart, lungs and immune system. Disruptions in circadian clocks,...

Eligibility Criteria

Inclusion

  • Healthy controls
  • Age 18-60
  • Intermediate circadian chronotype as determined by the Horne-Ostberg and Munich questionnaire
  • Habitual sleep start times between 9:30pm and 1am
  • Habitual sleep duration of 6-9 hours

Exclusion

  • History or current Diagnostic and Statistical Manual-V major psychiatric disorder
  • Use of psychoactive medications
  • Beck Depression inventory ≥ 16 indicating possible depression
  • A history or current diagnosis of a primary sleep disorder (insomnia, sleep apnea, circadian rhythm sleep disorder, restless legs)
  • Shift work or other types of self-imposed irregular sleep/wake cycles
  • History of, or concurrent unstable or serious medical illness
  • Allergy to heparin
  • Blindness or other visual impairment other than glasses

Key Trial Info

Start Date :

January 29 2015

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2017

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT02291003

Start Date

January 29 2015

End Date

September 30 2017

Last Update

August 31 2018

Active Locations (1)

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1

Northwestern University

Chicago, Illinois, United States, 60611