Status:
COMPLETED
Comprehensive Cardiac CT Versus Exercise Testing in Suspected Coronary Artery Disease (2)
Lead Sponsor:
Erasmus Medical Center
Conditions:
Stable Angina Pectoris
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Multi-center, randomized-controlled trial comparing a comprehensive cardiac CT protocol with standard stress testing in patients with stable chest pain complaints.
Detailed Description
Rationale: CT calcium and coronary lumen imaging allow efficient exclusion of coronary artery disease (CAD), but cannot assess the hemodynamic significance of obstructive findings. Addition of stress ...
Eligibility Criteria
Inclusion
- Men and women aged \>18 years.
- Chest pain symptoms suspicious of coronary heart disease.
- Pre-test probability of coronary artery disease \>10%
Exclusion
- History of CAD: prior myocardial infarction or revascularization procedure
- Contra-indication to radiation exposure (CT/SPECT): pregnancy
- Contra-indication to iodine contrast media: renal failure, iodine allergy
- Contra-indications to adenosine
- Inability or unwillingness to provide informed consent.
Key Trial Info
Start Date :
August 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2016
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT02291484
Start Date
August 1 2013
End Date
May 1 2016
Last Update
August 4 2016
Active Locations (4)
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1
Albert Schweizerzieknhuis
Dordrecht, Netherlands, 3318 AT
2
Maastricht University Medical Center
Maastricht, Netherlands, 6229 HX
3
Erasmus MC
Rotterdam, Netherlands, 3015CE
4
Maasstadziekenhuis
Rotterdam, Netherlands