Status:
UNKNOWN
Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair Surgery
Lead Sponsor:
Centre Hospitalier Universitaire de Besancon
Conditions:
Aortic Aneurysm, Abdominal
Pain
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The ETAP study aim to assess the effect of the addition of an ultrasound-guided transversus abdominis plane (TAP) block to a multimodal intravenous analgesia protocol on the postoperative pain control...
Detailed Description
The open repair of abdominal aortic aneurysm (AAA) is a painful surgery. Patients suffering from AAA are at high risk of perioperative cardiovascular and pulmonary complications. It has been previousl...
Eligibility Criteria
Inclusion
- ASA (American Society of Anesthesiologists) physical status 1, 2 or 3
- Elective surgery for open repair of an aortic abdominal aneurysm performed in the Vascular Surgery Unit of the University Hospital of Besancon
- Informed consent given
- Health medical insurance affiliation
Exclusion
- Poor adherence to protocol attended
- Incapacity to consent
- Pregnancy and/or breast feeding
- Endovascular repair of aortic abdominal aneurysm
- Emergent surgery of a rupture or a fissuration of aortic abdominal aneurysm
- Chronic medical treatment by clopidogrel if clopidogrel not stopped 5 days before surgery at least
- Chronic medical treatment by prasugrel if prasugrel not stopped 7 days before surgery at least
- Chronic medical treatment by ticlopidine, inhibitors of phosphodiesterase , inhibitors of glycoprotein IIb/IIIa, adenosine triphosphate analogs or thrombin receptor antagonists
- Congenital or acquired bleeding disorder
- Incapacity to use patient-controlled analgesia device
- Chronic opioid abuse or dependence
- Chronic renal failure defined as a clearance \< 30 ml/min
- Severe hepatic failure
- Other contraindications to ropivacaïne (allergy, medical history of porphyria, hypovolemia)
- Contraindications to acetaminophen
- Contraindications to morphine
Key Trial Info
Start Date :
January 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02292667
Start Date
January 1 2015
End Date
January 1 2019
Last Update
August 12 2016
Active Locations (1)
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1
CHU Besançon
Besançon, Doubs, France, 25000