Status:

COMPLETED

CardioBBEAT - Randomized Controled Trial to Evaluate the Health Economic Impact of Remote Patient Monitoring

Lead Sponsor:

Eckhard Nagel

Collaborating Sponsors:

German Federal Ministry of Education and Research

Conditions:

Chronic Heart Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The primary endpoint is the incremental cost effectiveness ratio (ICER), defined as the combined clinical endpoint "days alive and not in hospital nor stationary care per days in study" and the change...

Detailed Description

Between January 2010 and June 2013, 621 patients with left ventricular ejection fraction (LVEF) ≤ 40% were enrolled and randomly assigned to two study arms comprising usual care and a home telemonitor...

Eligibility Criteria

Inclusion

  • Confirmed diagnosis of Chronic Heart Failure (CHF) based on European Society of Cardiology (ESC) guidelines
  • Symptoms corresponding to New York Heart Association (NYHA) functional class II-IV
  • Left Ventricular Ejection Fraction (LVEF) ≤ 40%
  • American Heart Association (AHA) classification stage C or D
  • Age \> 18 years
  • Discharged after hospitalisation for worsening Chronic Heart Failure (CHF) within the last twelve months
  • Able to understand the German language
  • Sufficient eyesight to understand and follow the instructions communicated by the Motiva® platform
  • Willing and able to use the required hard- and software and maintain a patient diary
  • Residing within geographical reach of one of the ten study sites in order to receive additional treatment if required as well as follow-up consultation
  • Willingness to provide informed consent regarding benefits and risks related to the trial, and to sign a participation agreement for the installation of the telemedicine platform Motiva®

Exclusion

  • Myocardial infarction within the past four weeks
  • Heart surgery or any coronary intervention within the past eight weeks
  • Cardiogenic shock within the past four weeks
  • Intended cardiac surgery within the next six months or priority status on a waiting list for organ transplantation
  • Severe chronic and pulmonary illness with an immediate impact on the main outcome measures
  • Renal failure requiring dialysis
  • Dementia or other severe cognitive impairment
  • Psychiatric disorders rendering patients unable to participate in the trial
  • Discharged to or living in a geriatric clinic or a nursing home
  • Participation in another clinical trial

Key Trial Info

Start Date :

March 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2016

Estimated Enrollment :

621 Patients enrolled

Trial Details

Trial ID

NCT02293252

Start Date

March 1 2009

End Date

October 1 2016

Last Update

October 25 2016

Active Locations (1)

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University of Bayreuth

Bayreuth, Bavaria, Germany, 95444