Status:
COMPLETED
Planetary Habitat Simulation: Nutrition Studies
Lead Sponsor:
University of Nottingham
Collaborating Sponsors:
Jozef Stefan Institute
KTH Royal Institute of Technology
Conditions:
Hypoxia
Eligibility:
MALE
25-45 years
Phase:
NA
Brief Summary
A loss of body weight has been documented in lowland-living individuals when exposed to hypoxic environments, such as at high altitude, or under laboratory conditions. A reduction in appetite and ener...
Detailed Description
A loss of body weight has been documented in lowland-living individuals when exposed to hypoxic environments, such as at high altitudes, or under laboratory conditions. This weight loss has been attri...
Eligibility Criteria
Inclusion
- Physically and mentally healthy subjects
- Body mass index \< 25 kg/m2
- Height 158 - 190 cm
- Waist circumference \< 94 cm
- Volunteers that are able to declare their willingness to participate in the entire study
- Willing to be assigned randomly to the three groups
- Successfully passing the psychological and medical screening
- competent to sign informed consent
- Slovenian social insurance
- English language fluency
Exclusion
- Medication required that may interfere with the interpretation of the results
- Bone mineral density (as measured by DEXA) more than 1.5 standard deviations \< t score
- Recent sub-standard nutritional status
- Family history of thrombosis or positive response in thrombosis screening procedure.
- (Biochemical analysis of the following parameters: ATIII, High sensitive C-reactive protein, S-Akt., Factor V-Leiden, Prothrombin, Lupus-partial thromboplastin time, Factor II)
- History of: thyroid dysfunction, renal stones, diabetes, allergies, hypertension, hypocalcemia, uric acidaemia, lipidaemia, or hyperhomocysteinaemia
- Gastro-esophageal reflux disease or renal function disorder, Hiatus hernia
- History of medical illness
- Smoker within six months prior to the start of the study
- Abuse of drugs, medicine or alcohol
- Participation in another study up to two months before study onset
- No signed consent form before the onset of the experiment
- Blood donors in the past three months before the onset of the experiment
- Vegetarian and Vegans
- Migraines
- History of orthostatic intolerance
- History of vestibular disorders
- Claustrophobia
- metallic implants, osteosynthesis material
- Chronic back pain
Key Trial Info
Start Date :
March 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT02293772
Start Date
March 1 2012
End Date
October 1 2014
Last Update
March 15 2019
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