Status:
COMPLETED
Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity and Mortality
Lead Sponsor:
Institute of Liver and Biliary Sciences, India
Conditions:
Diastolic Dysfunction
Chronic Liver Disease
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Cirrhotic cardiomyopathy is defined as a chronic cardiac dysfunction in patients with cirrhosis. It is suspected that this specific cardiac dysfunction contributes to the onset of complications in liv...
Eligibility Criteria
Inclusion
- Patients with cirrhosis who have been diagnosed by clinical, biochemical,or histological (when available) criteria plus ultrasound imaging.
- Age range of 18-60 years
- Cirrhosis as diagnosed by histology or clinical, laboratory and USG (UltraSonography) findings,
- Upper GI bleed who are undergoing secondary endoscopic variceal ligation for eradication of varices
Exclusion
- Age \>60 years
- Chronic renal disease
- Pregnancy and peripartum cardiomyopathy
- Hypertension
- Coronary artery disease
- Valvular heart disease
- Sick sinus syndrome/ Pacemaker
- Cardiac rhythm disorder
- Hypothyroidism
- Hyperthyroidism
- Portal vein thrombosis
- Transjugular intrahepatic porto systemic shunt (TIPS) insertion
- Hepatocellular carcinoma
- Anemia Hb \< 8gm/dl in females, and \< 9 gm/dl in males
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2016
Estimated Enrollment :
189 Patients enrolled
Trial Details
Trial ID
NCT02294292
Start Date
July 1 2014
End Date
August 31 2016
Last Update
February 8 2018
Active Locations (1)
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1
Institute of Liver & Biliary Sciences
New Delhi, National Capital Territory of Delhi, India, 110070