Status:

TERMINATED

Excimer Laser Phototherapy Outcomes in the Treatment of Psoriasis

Lead Sponsor:

University of California, San Francisco

Conditions:

Psoriasis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to determine the best dosing strategy when using Excimer Laser to treat plaque-type psoriasis. In this study, half of the body's psoriasis will be treated with a new dosin...

Detailed Description

This is a randomized, assessor-blinded clinical trial to determine whether a novel plaque-based dosimetry strategy can improve the speed of response to excimer laser treatment in patients with plaque ...

Eligibility Criteria

Inclusion

  • Diagnosis of chronic plaque psoriasis for at least 6 months
  • Age ≥ 18 years
  • Body surface area affected ≤ 10 percent
  • Presence of at least one pair of bilateral target lesions with an area of at least 20 cm2 per target lesion. The bilateral target lesions must be present in the same category of anatomical region (e.g., bilateral lower extremities, bilateral upper extremities or bilateral trunk).

Exclusion

  • active or past history of erythrodermic psoriasis, guttate psoriasis, or pustular psoriasis
  • history of photosensitivity disorder
  • history of malignant melanoma
  • active, invasive non-melanoma skin carcinoma
  • Fitzpatrick Skin Type I
  • Subject has received ultraviolet B phototherapy or any topical anti-psoriatic therapy within two weeks prior to starting the study.
  • Subject has received systemic or topical psoralen-ultraviolet A photochemotherapy within four weeks prior to starting the study.
  • Subject has received biologic therapy within three months of starting the study.

Key Trial Info

Start Date :

January 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2017

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT02294981

Start Date

January 1 2016

End Date

September 1 2017

Last Update

June 18 2020

Active Locations (1)

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1

UCSF Psoriasis Skin and Treatment Center

San Francisco, California, United States, 94118