Status:
COMPLETED
Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis
Lead Sponsor:
San Antonio Military Medical Center
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Osteoarthritis is a disabling disease of the joint spaces and has a high impact on society due to the amount of people who are affected by the disease. Nonoperative management is a mainstay of therapy...
Detailed Description
Subject Population: Adult patients, age 18-90 years old who satisfy the inclusion criteria and do not meet the exclusion criteria will be enrolled from the Orthopaedics Clinic at San Antonio Military ...
Eligibility Criteria
Inclusion
- Subject must be at least 18 years of age and no older than 90 years of age; of either gender
- Radiographic evidence of symptomatic osteoarthritis in one or bilateral knees. Osteoarthritis will be defined as pain with weight-bearing at the tibiofemoral and/or patellofemoral articulation together with radiographic findings as described below.
- At the painful articulation, radiographic evidence of Kellgren-Lawrence
- Grade 2: definite osteophytes and possible narrowing of joint cartilage associated with sclerosis of subchondral bone or,
- Grade 3: moderate multiple osteophytes, definite narrowing of the joint space, small pseudocystic areas with sclerotic walls in the subchondral bone, possible deformity of bone ends or,
- Grade 4: large osteophytes, marked narrowing of joint space, severe sclerosis and altered shape of the bone ends.
- Subject agrees to participate in follow-up evaluations and complete outcome score sheets (post-injection, 2 weeks, 6 weeks, 3 months and 6 months).
Exclusion
- Any inflammatory or neuropathic arthropathy
- Insufficiency of the collateral ligaments or cruciate ligaments
- Current infection
- Recent injection (\<3 months)
- Pregnant/lactating (β-human chorionic gonadotropin pregnancy test will be completed prior to injection)
- Allergy or hypersensitivity to the study medications
- Currently taking any anti-coagulation medications
- Subject is unable to make his/her own decision regarding the informed consent
- Subject is unable to read/understand English
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT02295189
Start Date
January 1 2013
End Date
June 1 2014
Last Update
November 20 2014
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.