Status:
COMPLETED
Molecular Analysis of IgE Antibodies in Walnut Allergic Patients
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
Paul Ehrlich Institute Langen
Hospital Clinic of Barcelona
Conditions:
Food Allergy
Eligibility:
All Genders
1-70 years
Phase:
NA
Brief Summary
Accurate diagnosis of food allergy depends on the identification of the causative allergenic molecule(s). The proposed study intends to investigate and compare the pattern of IgE antibody sensitisatio...
Detailed Description
Accurate diagnosis of food allergy depends on the identification of the causative allergenic molecule(s). Thus, full characterization of the major allergens of walnut and their clinical importance is ...
Eligibility Criteria
Inclusion
- Signed informed consent
- Group A: positive case history of allergic reaction(s) to walnut
- Group B: positive case history of allergy to birch, grass or olive pollen and no case history of allergic reaction(s) to walnut
- Group C: no case history of atopic disease
Exclusion
- Known pregnancy
- Breast-feeding of infant
- Treatment with the following drugs (or shortest interval between last treatment and food challenge or SPT):
- corticosteroids (2 weeks): applied systemically, to the nose or locally on the skin test area.
- antihistamines (3 days) except hydroxyzine (10 days)
- betablocker agents (1 day)
- angiotensin converting enzyme inhibitors (2 days)
- Any major organic or infectious disease
Key Trial Info
Start Date :
December 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2017
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT02295267
Start Date
December 1 2012
End Date
March 1 2017
Last Update
May 11 2017
Active Locations (1)
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1
Allergy Unit, Department of Dermatology, University Hospital
Zurich, Switzerland, 8091