Status:
COMPLETED
Determinism of the Mechanism of Action of Specific Immunotherapy in Hymenoptera Venom Allergy
Lead Sponsor:
University Hospital, Rouen
Conditions:
Hymenoptera Allergy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Currently, most of the protocols used for desensitization to Hymenoptera venoms consist of a very rapid increase in doses of venom extracts administered during the SIT in a day without systemic reacti...
Eligibility Criteria
Inclusion
- Patients over 18 years and below 75 years age
- Patient who presented a generalized allergic reaction after an puncture of a hymenoptera
- Patient with positive skin tests against the venom of a hymenoptera
- Patient with positive specific IgE against the venom of a hymenoptera • to which an indication of accelerated desensitization was chosen in day hospitalization
- Information and consent signed by the patient
- Patient affiliated to french social security system
- For women of childbearing age, taking an effective contraceptive.
Exclusion
- Patients with the following diseases: Mastocytosis, systemic infection or hospitalization within 4 weeks before inclusion, chronic inflammatory disease, cancer, unbalanced asthma, immune deficiency
- Patients on beta-blocker, following another specific immunotherapy, or ongoing immunosuppressive therapy.
- Pregnant or lactating
- People placed under judicial protection
- Patient participating or having participated in another biomedical research within six months
Key Trial Info
Start Date :
March 23 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 12 2018
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT02295488
Start Date
March 23 2015
End Date
April 12 2018
Last Update
October 25 2019
Active Locations (1)
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1
Rouen University Hospital
Rouen, France, 76031