Status:

TERMINATED

Miradry Treatment for Focal Axillary Hyperhidrosis

Lead Sponsor:

Johns Hopkins University

Conditions:

Axillary Hyperhidrosis

Eligibility:

All Genders

18-29 years

Phase:

NA

Brief Summary

Primary hyperhidrosis is a pathological condition characterized by the idiopathic and excessive secretion of sweat beyond normal physiological demand and is localized at particular foci such as the fa...

Detailed Description

Primary Objective: 1. To evaluate the effectiveness of the miraDry ® treatment system for psychosocial functioning in patients heavily affected by axillary hyperhidrosis. Secondary Objectives: 2....

Eligibility Criteria

Inclusion

  • This study will recruit patients diagnosed with focal hyperhidrosis with a known diagnosis of primarily axillary localization.
  • We will only enroll patients available for both treatment visits. Availability for follow-up visit is optional.
  • Only patients between the ages of 18 and 29 years when the first HHIQ is administered will be eligible.
  • The upper age limit was so determined because patients over 29 years often present with psychopathology which is far more recalcitrant to correction of any kind regardless of effectiveness because of the duration of the condition.
  • The lower age limit was so determined because 18 years and up are the ages for which the miraDry ® procedure has been approved for use by the FDA.
  • All participants will be screened using the Hyperhidrosis Disease Severity Scale (HDSS).
  • Only patients reporting their condition as a 3 out of 4 or higher on the HDSS will be eligible for study because preliminary data suggests effective detection of psychological changes only at higher reported levels of sweating severity.
  • A patient's previous non-invasive treatment course, including but not limited to prescription of psychiatric medication and topical therapies, will not justify exclusion from this study.

Exclusion

  • Patients who are unable to provide informed consent, have known allergies to lidocaine, hibiclens with 4% chlorhexidine, and/or epinephrine, are pregnant (as determined by self-reporting), are unable to take oral antibiotics or antiseptic washes, have heart pacemakers or other electronic device implants, and who need supplemental oxygen are not eligible to participate in this study

Key Trial Info

Start Date :

November 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2019

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT02295891

Start Date

November 1 2014

End Date

December 1 2019

Last Update

May 30 2025

Active Locations (1)

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1

Johns Hopkins University

Baltimore, Maryland, United States, 21287