Status:

COMPLETED

Comparative Effectiveness of Antibiotics for Respiratory Infections

Lead Sponsor:

Children's Hospital of Philadelphia

Conditions:

Acute Otitis Media

Acute Sinusitis

Eligibility:

All Genders

6-12 years

Brief Summary

The purpose of this study is to identify and use patient centered outcomes to compare narrow-spectrum and broad-spectrum antibiotics for the treatment of common acute respiratory tract infections (ART...

Detailed Description

Outpatient, ARTIs account for the vast majority of antibiotic exposure to children, and roughly half of these antibiotic prescriptions are inappropriate. Although unnecessary antibiotic prescribing fo...

Eligibility Criteria

Inclusion

  • We included children between six months and 12 years old, diagnosed with an ARTI (acute otitis media, acute sinusitis, Group A streptococcal \[GAS\] pharyngitis) using International Classification of Diseases diagnosis codes and prescribed an antibiotic. For GAS pharyngitis, the child also had a positive rapid streptococcal test.

Exclusion

  • Diagnosed with multiple ARTIs
  • Diagnosed with another non-ARTI bacterial infection
  • Prescribe antibiotics in the past 30 days
  • Non-English speaking families
  • If GAS pharyngitis diagnosis, age \< 3 years

Key Trial Info

Start Date :

January 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2016

Estimated Enrollment :

2472 Patients enrolled

Trial Details

Trial ID

NCT02297815

Start Date

January 1 2014

End Date

April 1 2016

Last Update

July 8 2019

Active Locations (1)

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1

The Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

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