Status:
COMPLETED
Effects of Low Calorie Sweeteners on Dietary Intakes, Hunger, Appetite and Satiety
Lead Sponsor:
The Coca-Cola Company
Collaborating Sponsors:
CreaBIO
Conditions:
Eating Behavior
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Although there is evidence that low calorie sweeteners (LCS) do not stimulate hunger or appetite, divergent opinions appear regularly both in the scientific literature and in the popular press. The go...
Detailed Description
The study will be a monocentric randomized controlled open trial including two parallel groups to examine effects of LCS beverages as compared to water on daily intakes of energy and macronutrients. T...
Eligibility Criteria
Inclusion
- Body Mass Index: Lower limit 18 kg/m²; Upper limit 28 kg/m²; weight stable within ± 3 kg in the last 6 months
- Habitual energy intake within the 95% confident interval of the reference energy intake for the French population (as provided by the INCA 2 survey
- Must not be a regular drinker of LCS beverages (less than once a week no more than every 15 days) and be willing to use LCS according to protocol
- For female participants: not pregnant, not breast feeding, planning to become pregnant during the study or on contraception since at least 3 months (regular 28-day cycle)
- Subject registered with the French Social Security.
Exclusion
- Currently diagnosed somatic pathology
- On medication affecting metabolism, weight, energy intake, or energy expenditure in the last 6 months
- Major psychiatric disorder, particularly eating disorders as defined by the Diagnostic and Statistical Manual od Mental Disorders-IV
- Rejection of sweet foods or drinks as revealed by the diet history
- Smoking subject planning to stop smoking in the next 3 months
- Subjects suffering from food allergies or intolerance
- Subject not capable of understanding the constraints of the study and who not agree to abide
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2016
Estimated Enrollment :
170 Patients enrolled
Trial Details
Trial ID
NCT02297880
Start Date
October 1 2014
End Date
March 1 2016
Last Update
February 9 2017
Active Locations (1)
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1
CreaBio Rhône-Alpes laboratory, 9 avenue du Professeur Fleming
Givors, Lyon, France, 69700