Status:
COMPLETED
An fMRI Study of Satiation in Healthy Volunteers.
Lead Sponsor:
University of Birmingham
Collaborating Sponsors:
University of Oxford
Conditions:
Appetite
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
To our knowledge no study has assessed the effects of a meal on neural responses to food cues and compared this with a condition simulating natural inter-meal hunger levels. This is important, as the ...
Detailed Description
We hypothesized that satiation would be associated with decreased brain activity across brain regions involved in both appetite and reward such as ventromedial prefrontal cortex, orbitofrontal cortex,...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Sufficiently fluent in English to understand the task and the instructions
Exclusion
- Currently taking medication
- Past or current depression/dieting,
- Smokers
- Food allergies
- Diabetes
- Pregnancy
- BMI score outside the normal range
- Any contraindications to fMRI scanning (e.g. pacemakers, mechanical heart valve, hip replacement, metal implants)
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT02298049
Start Date
July 1 2010
End Date
December 1 2010
Last Update
November 21 2014
Active Locations (1)
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1
University of Birmingham
Birmingham, West Midlands, United Kingdom, B15 2TT