Status:
TERMINATED
Metabolomic Analysis of Systemic Sclerosis
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Scleroderma (Limited and Diffuse)
Undifferentiated Connective Tissue Disease
Eligibility:
All Genders
18+ years
Brief Summary
Currently investigators do not have diagnostic and prognostic markers for SSc which almost always starts with a vascular disease (Raynaud's disease) isolated for several years. The primary purpose is...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Group 1 (scleroderma) : Patients with ACR / EULAR (2012) and / or criteria of Leroy and Medsger (2001)
- Group 2 (UCDT) : Patients with criteria proposed by Mosca et al. (1998)
- Group 3 (Raynaud) : Patients with primary and isolated Raynaud disease
- Group 4 (vascular disease) : Patients with type 2 diabetes, occlusive vascular disease, history of myocardial infarction or ischemic stroke
- Group 5 (healthy control) : healthy subjects (no sign of connective tissue disease, no Raynaud, no vascular disease)
- Exclusion criteria:
- Group 1 (scleroderma) : Patients not fulfilling ACR / EULAR (2012) and / or criteria of Leroy and Medsger (2001), or with another auto-immune disease
- Group 2 (UCDT) : Patients not fulfilling criteria proposed by Mosca et al. (1998)
- Group 3 (Raynaud) : Patients with no Raynaud disease
- Group 4 (vascular disease) : Patients with no vascular disease
- Group 5 (healthy control) : Patients with sign of connective tissue disease, Raynaud, or vascular disease)
Exclusion
Key Trial Info
Start Date :
December 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 24 2025
Estimated Enrollment :
121 Patients enrolled
Trial Details
Trial ID
NCT02298777
Start Date
December 1 2014
End Date
April 24 2025
Last Update
August 8 2025
Active Locations (4)
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1
CHU
Dijon, France, 21079
2
Hôpitaux privés de Metz
Metz, France, 57045
3
CHU
Reims, France, 51092
4
Hôpitaux Universitaires de Strasbourg
Strasbourg, France, 67000