Status:

UNKNOWN

Predicting the Risk of Post-operative Delirium: Use of Neuropsychology, Serum and CSF Biomarkers and Genetics to Predict Risk of Post-operative Delirium

Lead Sponsor:

Belfast Health and Social Care Trust

Conditions:

Delirium

Eligibility:

All Genders

65+ years

Brief Summary

The purpose of the study is to determine if pre-operative neuropsychological characteristics, apolipoprotein E4 status and/or cerebrospinal fluid (CSF) and serum biomarkers can predict those most at r...

Eligibility Criteria

Inclusion

  • living at home
  • undergoing primary, elective hip or knee arthroplasty
  • spinal anaesthetic with intrathecal diamorphine anticipated

Exclusion

  • neurological, hearing or visual disability affecting ability to participate in study
  • known neurodegenerative condition eg dementia, Parkinson's disease, multiple sclerosis

Key Trial Info

Start Date :

March 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2025

Estimated Enrollment :

316 Patients enrolled

Trial Details

Trial ID

NCT02299037

Start Date

March 1 2012

End Date

February 1 2025

Last Update

December 26 2023

Active Locations (1)

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1

Centre for Public Health, Queen's University Belfast

Belfast, United Kingdom, BT12 6BA