Status:

UNKNOWN

Effect of Valsartan vs Perindopril on HOMA-IR Index in Patients With Chronic Kidney Disease

Lead Sponsor:

Chinese PLA General Hospital

Conditions:

Chronic Kidney Disease

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare the effect of valsartan and perindopril on HOMA-IR Index in patients with chronic kidney disease.

Detailed Description

eligiable volunteers are administrated single-dose over the period I and II (crossover) of Valsartan (80mg) as of Perindopril (4mg). Every time before and after each medication, HOMA-IR index and oth...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of chronic kidney disease
  • Serum creatinine:1\~3mg/dl

Exclusion

  • Diabetes
  • Patients treated with corticosteroids or immunosuppressants
  • BMI\>30kg/m2
  • SP\>180mmHg, DP\>110mmHg
  • Patients with serious medical problems requiring specific medical treatment

Key Trial Info

Start Date :

November 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2015

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02299310

Start Date

November 1 2014

End Date

December 1 2015

Last Update

December 2 2014

Active Locations (1)

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Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853