Status:

COMPLETED

Study to Evaluate the Janssen Autism Knowledge Engine in Children and Adults With Autism Spectrum Disorder

Lead Sponsor:

Janssen Research & Development, LLC

Conditions:

Autism Spectrum Disorder

Eligibility:

All Genders

3+ years

Brief Summary

The purpose of this study is to assess the usability of the Janssen Autism Knowledge Engine (JAKE) as a system to monitor clinical outcomes in autism spectrum disorder (ASD) (severe abnormalities in t...

Detailed Description

This is an observational (study in which participants identified as belonging to study groups are assessed for biomedical or health outcomes) and prospective (study following participants forward in t...

Eligibility Criteria

Inclusion

  • Participants can receive behavioral and/or pharmacologic treatments for Autism Spectrum Disorder (ASD) and comorbid disorders during the course of the study
  • Parents or legally acceptable representatives must speak and understand English
  • Participants must live with a parent or primary caregiver or, if not, they must either (A) spend at least 3 hours a day for at least 4 days each week or, (B) spend at least 3 weekends a month with a parent or primary caregiver
  • Parents or legally acceptable representatives must possess (A) a portable electronic device capable of running the Janssen Autism Knowledge Engine (JAKE) application and connecting to the internet, and (B) a laptop or desktop computer connected to the internet
  • In the opinion of the Investigator, participant and parents must be capable of completing all procedures and tasks of the study
  • Diagnosis of ASD made or confirmed by the Investigator according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) criteria using a DSM V checklist and at least a 'mild' rating on the Child Autism Rating Scale 2 (CARS-2)

Exclusion

  • Lab sites only: Measured composite score on the Vineland Adaptive Behavior Scales (VABS) of less than 60
  • History of or current significant medical illness that the Investigator considers should exclude the participant
  • Psychological and/or emotional problems which would render the informed consent invalid or limit the ability of the participant to comply with the study requirements
  • Any condition that in the opinion of the Investigator would complicate or compromise the study, or the wellbeing of the participant; for example, visual problems that would impede eye tracking or viewing the stimuli or hearing problems that would impede hearing auditory stimuli
  • Employees of the Investigator or study center, with direct involvement in the proposed study or other studies under the direction of that Investigator or study center, as well as family members of the employees or the Investigator

Key Trial Info

Start Date :

September 30 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 24 2015

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT02299700

Start Date

September 30 2014

End Date

April 24 2015

Last Update

October 23 2017

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Boston, Massachusetts, United States

2

Toms River, New Jersey, United States

3

Durham, North Carolina, United States