Status:

RECRUITING

Cerebellar Mutism Syndrome Study

Lead Sponsor:

Rigshospitalet, Denmark

Collaborating Sponsors:

Odense University Hospital

Aarhus University Hospital

Conditions:

Infratentorial Neoplasms

Mutism

Eligibility:

All Genders

Up to 18 years

Brief Summary

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the pur...

Detailed Description

Background: Cancer accounts for 22 % of all deaths among children in Europe and is thus the leading non-traumatic pediatric cause of death. Central nervous system (CNS) tumours constitute 25% of all ...

Eligibility Criteria

Inclusion

  • Age \< 18 years at the date of first imaging showing this tumour
  • Tumour in the cerebellum/4th ventricle/brainstem with intention to treat with surgical resection or open biopsy. Second and further surgeries are also included.
  • Informed consent from custodial parent(s)

Exclusion

  • None

Key Trial Info

Start Date :

October 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT02300766

Start Date

October 1 2014

End Date

December 31 2028

Last Update

September 26 2025

Active Locations (30)

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Page 1 of 8 (30 locations)

1

Medical University of Vienna

Vienna, Austria

2

University Hospital Leuven

Leuven, Belgium

3

Motol University Hospital

Prague, Czechia

4

Aalborg University Hospital

Aalborg, Denmark, 9100