Status:
RECRUITING
Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry
Lead Sponsor:
University of Kansas Medical Center
Conditions:
Breast Cancer
Hereditary Breast and Ovarian Cancer
Eligibility:
All Genders
Brief Summary
PROGECT is a registry for patients with Triple Negative breast cancer (TNBC) or patients who have an identified germline mutations (such as a mutation on the BRCA1 or BRCA2 genes).
Detailed Description
This study is being done to collect cancer-related information from patients with triple negative breast cancer and patients with hereditary genetic mutations. This information will help us better und...
Eligibility Criteria
Inclusion
- Inclusion criteria include:
- Triple Negative Breast Cancer
- ER/PR \<10% and HER negative per current ASCO/CAP guidelines
- Stages I-IV
- Any age at diagnosis
- Patient must be within 5 years of diagnosis
- Eligible regardless of genetic testing status
- Genetic testing recommended for patients meeting NCCN and Medicare guidelines
- AND/OR
- Germline mutation Carriers
- Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53, -PALB2 etc) are eligible regardless of type/site of cancer
- Healthy patients harboring mutations also eligible
- There is no time limit from the time of diagnosis of cancer and enrollment.
- Eligible regardless of personal history of cancer
- Exclusion Criteria include:
- Triple Negative Breast Cancer -Patient is not within five years of diagnosis
- Germline mutation Carriers:
- Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor polymorphism"
Exclusion
Key Trial Info
Start Date :
March 22 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT02302742
Start Date
March 22 2011
End Date
December 1 2026
Last Update
October 6 2025
Active Locations (11)
Enter a location and click search to find clinical trials sorted by distance.
1
Hays Medical Center Dreiling-Schmidt Cancer Institute
Hays, Kansas, United States, 67601
2
KCCC West
Kansas City, Kansas, United States, 66112
3
KCCC Overland Park
Overland Park, Kansas, United States, 66210
4
Overland Park Regional Medical Center
Overland Park, Kansas, United States, 66215