Status:

UNKNOWN

Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT

Lead Sponsor:

University of Siena

Collaborating Sponsors:

IBSA Institut Biochimique SA

Conditions:

Thyroiditis Autoimmune

Eligibility:

FEMALE

18-65 years

Phase:

PHASE2

Brief Summary

Over the past 10 years, several clinical studies have suggested that selenium supplementation may influence the natural history of AIT. Recently, Interferon gamma (IFNγ)-inducible chemokines (CXCL-9, ...

Eligibility Criteria

Inclusion

  • Diagnosis of chronic autoimmune thyroiditis defined by positivity of anti thyroperoxidase and/or anti thyroglobulin antibodies (\> or = 100 U/l) and thyroid hypoechogenicity

Exclusion

  • Presence of other thyroid disease but micronodules
  • History of the malignancy in the past 5 years
  • Drugs affecting immune system and/or thyroid function
  • Pregnancy detected during screening or follow-up.

Key Trial Info

Start Date :

December 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2015

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02302768

Start Date

December 1 2012

End Date

January 1 2015

Last Update

November 27 2014

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