Status:
COMPLETED
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Lead Sponsor:
Clearside Biomedical, Inc.
Conditions:
Macular Edema
Retinal Vein Occlusion
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
A phase 2, multicenter, randomized, active-controlled, masked, parallel arm study designed to evaluate the safety and efficacy of a single suprachoroidal injection of CLS-TA, triamcinolone acetonide i...
Detailed Description
A randomized, masked, controlled trial of safety and efficacy of suprachoroidal CLS-TA in combination with intravitreal aflibercept in subjects with macular edema following retinal vein occlusion
Eligibility Criteria
Inclusion
- diagnosis of macular edema following RVO
- History of ME ≤ 12 months
- 20-70 letters inclusive BCVA using ETDRS
Exclusion
- has had an IVT injection of anti-VEGF for RVO in the study eye
- has had a corticosteroid injection in the past 3 months in the study eye
- any uncontrolled ophthalmic condition in the study eye other than RVO
Key Trial Info
Start Date :
January 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2016
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT02303184
Start Date
January 1 2015
End Date
March 1 2016
Last Update
February 8 2021
Active Locations (14)
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1
Phoenix, Arizona, United States, 85014
2
Beverly Hills, California, United States, 90211
3
San Diego, California, United States, 92037
4
Boynton Beach, Florida, United States, 33426