Status:

COMPLETED

Kinetics of YKL-40 Protein in Serum of Cystic Fibrosis Patients

Lead Sponsor:

Institut de Recherches Cliniques de Montreal

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

18+ years

Brief Summary

YKL-40 is proposed as a biomarker of various inflammatory disease diabetes and lung disease including cystic fibrosis. In those cross-sectional studies, a unique value of YKL-40 is used to correlate w...

Detailed Description

Observational prospective cohort: The primary objective of the study is to determine if variation of YKL-40 concentration (in blood or sputum) over 24 months will correlate with the biological or clin...

Eligibility Criteria

Inclusion

  • man and woman ≥ 18 ans.
  • documented CF diagnostic (sweat test or genotype).
  • FEV1 ≥ 25%
  • Stable: no infection in the last two weeks before the visit.

Exclusion

  • 1\. Exacerbation with respiratory symptoms with ou without hospitalization in the last two weeks 2. Exacerbation treated with IV antibiotics. 3. Patients with B. Cepacia
  • \-

Key Trial Info

Start Date :

May 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 20 2018

Estimated Enrollment :

188 Patients enrolled

Trial Details

Trial ID

NCT02305784

Start Date

May 1 2015

End Date

June 20 2018

Last Update

January 31 2019

Active Locations (1)

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CRIMontreal

Montreal, Quebec, Canada, H2W 1R7