Status:

COMPLETED

Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in the Treatment of First Episode Nonaffective Psychosis

Lead Sponsor:

Fundación Marques de Valdecilla

Collaborating Sponsors:

Centro de Investigación Biomédica en Red de Salud Mental

Instituto de Investigación Marqués de Valdecilla

Conditions:

Schizophrenia

Psychotic Disorders

Eligibility:

All Genders

15-60 years

Phase:

PHASE4

Brief Summary

The selection of antipsychotic in early stages of the illness is mainly determined by its clinical effectiveness. Second generation antipsychotics (SGAs) are the first line drug treatment for individu...

Detailed Description

Study setting and financial support: data for the present investigation were obtained from an ongoing epidemiological and three-year longitudinal intervention program of first-episode psychosis (PAFIP...

Eligibility Criteria

Inclusion

  • 15-60 years.
  • Living in the catchment area.
  • Experiencing their first episode of psychosis.
  • No prior treatment with antipsychotic medication or, if previously treated, a total life time of adequate antipsychotic treatment of less than 6 weeks.
  • Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for brief psychotic disorder, schizophreniform disorder, schizophrenia, or schizoaffective disorder.

Exclusion

  • Meeting DSM-IV criteria for drug dependence
  • Meeting DSM-IV criteria for mental retardation
  • Having a history of neurological disease or head injury.

Key Trial Info

Start Date :

October 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2014

Estimated Enrollment :

203 Patients enrolled

Trial Details

Trial ID

NCT02305823

Start Date

October 1 2005

End Date

May 1 2014

Last Update

March 14 2017

Active Locations (1)

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1

University Hospital Marques de Valdecilla

Santander, Cantabria, Spain, 39008