Status:
ENROLLING_BY_INVITATION
Registry of Patients With Hypophosphatasia
Lead Sponsor:
Alexion Pharmaceuticals, Inc.
Conditions:
Hypophosphatasia (HPP)
Eligibility:
All Genders
Brief Summary
In this prospective, observational, long term registry patients of all ages with a diagnosis of hypophosphatasia (HPP) are followed at participating sites in multiple countries.
Detailed Description
The HPP Registry is an observational, prospective, long-term registry designed to collect data on HPP epidemiology, disease history, clinical course, symptoms and burden of disease from patients of al...
Eligibility Criteria
Inclusion
- Male and female participants, of any age, with a confirmed diagnosis of HPP.
- Participant must have documented alkaline phosphatase (ALP) activity below the lower limit of normal for age and sex, or a documented ALPL gene mutation.
- Participant or legal representative is able to read and/or understand the informed consent and study questionnaires in the local language.
- Signed informed consent and medical records release by the patient or legal representative. Patient or patient's parent/legal representative must be willing and able to give written informed consent, and the patient must be willing to give written informed assent, if appropriate and required by local regulations.
Exclusion
- Currently participating in an Alexion-sponsored clinical trial. Enrollment in the Registry will not exclude a patient from enrolling in a future clinical trial.
Key Trial Info
Start Date :
January 20 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2031
Estimated Enrollment :
1571 Patients enrolled
Trial Details
Trial ID
NCT02306720
Start Date
January 20 2015
End Date
December 31 2031
Last Update
December 18 2025
Active Locations (65)
Enter a location and click search to find clinical trials sorted by distance.
1
Research Site
Centennial, Colorado, United States, 80112
2
Research Site
Hartford, Connecticut, United States, 06106
3
Research Site
Tampa, Florida, United States, 33606
4
Research Site
Decatur, Georgia, United States, 30033