Status:

COMPLETED

Ketamine For Acute Treatment of Pain in Emergency Department

Lead Sponsor:

The Brooklyn Hospital Center

Conditions:

Pain

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

The aim of the study is to compare the safety \& efficacy of low dose ketamine and morphine versus morphine alone for acute generalized pain in the Emergency Department (ED). The investigators are als...

Detailed Description

The aim of the study is to compare the safety \& efficacy of low dose ketamine and morphine versus morphine alone for acute generalized pain in the Emergency Department (ED). The is a randomized doubl...

Eligibility Criteria

Inclusion

  • Patients 18 years old and older presenting with acute generalized pain
  • Describes pain to be greater than or equal to 3 on the Visual Analogue Scale (VAS)
  • Provides informed consent

Exclusion

  • Patients who are admitted to the hospital
  • Severe hypertension(≥180/100)
  • Presence of or suspected for traumatic head injury with or without loss of consciousness
  • Presence of or suspected for myocardial ischemia
  • Presence of or suspected alcohol intoxication
  • Hemodynamic instability
  • History of schizophrenia
  • History of Sickle cell crisis / presenting with acute sickle cell crisis
  • History of or suspected recreational substance abuse
  • History of or suspected diagnosis of headache or migraine
  • History of or suspected diagnosis increase in intracranial/intraocular pressure
  • Known or suspected pregnancy
  • Allergy to ketamine or morphine
  • Administration of opioids in previous 4 hours
  • Patients with language barriers or in altered mental status who are unable to describe pain
  • Patients weighing over 166kg

Key Trial Info

Start Date :

January 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2015

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02306759

Start Date

January 1 2015

End Date

November 1 2015

Last Update

August 9 2017

Active Locations (1)

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1

The Brooklyn Hospital Center

Brooklyn, New York, United States, 11201