Status:

COMPLETED

PK Analysis of Piperacillin in Septic Shock Patients

Lead Sponsor:

University of Aarhus

Conditions:

Septic Shock

Eligibility:

All Genders

18+ years

Brief Summary

Antibiotic dosing in septic shock patients poses a challenge for clinicians due to the pharmacokinetic changes seen in this population. Piperacillin/tazobactam is often used for empirical treatment, a...

Detailed Description

Early appropriate antimicrobial therapy is of utmost importance for reducing mortality in critically ill patients with sepsis and septic shock. Patophysiological changes associated with the septic pro...

Eligibility Criteria

Inclusion

  • Treatment with piperacillin/tazobactam for less than 24 hours. Treatment with noradrenaline. -

Exclusion

  • Renal replacement therapy. Age under 18.
  • \-

Key Trial Info

Start Date :

September 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2015

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT02306928

Start Date

September 1 2014

End Date

January 1 2015

Last Update

February 11 2016

Active Locations (1)

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1

Department of anesthesiology and intensive care, Aarhus University Hospital

Aarhus N, Denmark, 8200