Status:

COMPLETED

A Study of 99m Tc Pertechnetate Produced in High Energy Cyclotron in Patients With Thyroid Scan Indication

Lead Sponsor:

Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Conditions:

Autoimmune Thyroid Disease

Congenital Hypothyroidism

Eligibility:

All Genders

18-80 years

Brief Summary

Prospective, open label single site study to demonstrate the safety and efficacy of Tc-99m pertechnetate produced by high energy cyclotron at CHUS.

Detailed Description

The proposed clinical trial will be a prospective, case-controlled Phase I, open label, single site study. The first 10 consecutively enrolled patients will receive CYCLOTEC standard procedure thyroid...

Eligibility Criteria

Inclusion

  • Prescribed thyroid scan
  • Provided written informed consent prior to participation
  • Biochemical parameters within 5 times of the normal limits for age
  • WBC count \> 3.0/μL
  • ANC count 1.5/μL
  • Platelets \> 75,000/μL
  • Haemoglobin \> 10 g/dL
  • Karnofsky Performance Scale score \> 50

Exclusion

  • Nursing or pregnant females
  • Biochemical parameters as measured outside 5 times the normal limits for age within 14 days of the scan
  • WBC \< 3.0/μL
  • ANC \< 1.5/μL
  • Platelets \< 75,000/μL
  • Haemoglobin \< 10 g/dL
  • Unable and unwilling to follow instructions and comply with the protocol
  • Unable or unwilling to provide written informed consent prior to participation in the study
  • Karnofsky Performance Scale score \< 50

Key Trial Info

Start Date :

September 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 31 2016

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT02307175

Start Date

September 1 2014

End Date

October 31 2016

Last Update

December 4 2017

Active Locations (1)

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Centre hospitalier universitaire de Sherbrooke

Sherbrooke, Quebec, Canada, J1H 5N4