Status:
COMPLETED
PPV to Guide Fluid Management in the PICU
Lead Sponsor:
University of North Carolina, Chapel Hill
Conditions:
Sepsis
Systemic Inflammatory Response Syndrome
Eligibility:
All Genders
Up to 17 years
Phase:
NA
Brief Summary
Children who are critically ill often require large amounts of fluid during their acute illness. It has been shown in multiple studies that appropriate administration of fluid decreases morbidity and ...
Detailed Description
In pediatric critical care, it is difficult to discern a patient's intravascular fluid status (hypovolemia, hypervolemia, euvolemia). Often, pediatric sepsis patients exhibit profound hypovolemia and ...
Eligibility Criteria
Inclusion
- Admission to the University of North Carolina pediatric critical care unit, includes all patients admitted to the pediatric critical care service as well as all post-operative patients.
- No limitations for age or gender.
- Patient requires standard mechanical ventilation.
- Patient has an arterial line in place.
Exclusion
- Patient not mechanically ventilated.
- Patient does not have arterial line placed.
- Patient requires extracorporeal life support.
- Patient requires placement on high frequency oscillatory ventilation.
- Pulse pressure variation unable to be obtained on monitor.
- Patient has open chest.
- Patient has arrhythmias.
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02308371
Start Date
November 1 2014
End Date
June 1 2016
Last Update
January 2 2017
Active Locations (1)
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1
University of North Carolina
Chapel Hill, North Carolina, United States, 27514