Status:
COMPLETED
Clindamycin Once a Day in Septic Abortion
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Septic Abortion
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
Septic abortion is a serious condition. Women with septic abortion are treated with clindamycin plus gentamicin using divided doses, i.e., thrice a day. The objective of this study is to compare the ...
Detailed Description
Obstetric infections are very common, especially in developing countries, as a consequence of the practice of unsafe abortion. In these countries, an estimated five million women each year are hospita...
Eligibility Criteria
Inclusion
- Women with clinical diagnosis of septic abortion: Briefly, a suspicion of infected/septic abortion was confirmed by the presence of at least one of the following clinical signs: a history of intrauterine manipulation with contaminated objects; foul-smelling vaginal discharge; purulent discharge from the cervix; signs of peritoneal irritation; leukocytosis (leukocyte count \> 14,000/mL); fever (temperature ≥ 37.8°C); or signs of a systemic inflammatory response, including tachycardia (heart rate \> 110 bpm), tachypnoea (respiratory rate \> 30 breaths/min), arterial hypotension (systolic blood pressure \< 90 mmHg), oliguria, cyanosis, or pallor.
Exclusion
- Refuse to participate in the study
- Use of antibiotics with 1 week prior randomization
- Known allergy to clindamycin or gentamycin
Key Trial Info
Start Date :
December 17 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
202 Patients enrolled
Trial Details
Trial ID
NCT02309346
Start Date
December 17 2014
End Date
December 31 2023
Last Update
December 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90035-003