Status:
UNKNOWN
Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Idiopathic Hypogonadotropic Hypogonadism
Eligibility:
MALE
16-35 years
Phase:
PHASE4
Brief Summary
Idiopathic hypogonadotropic hypogonadism (IHH) is the most common disorders of sex development (DSD).Therapy for IHH includes hormone replacement therapy, gonadotropin therapy and pulsed infusion of g...
Detailed Description
Idiopathic hypogonadotropic hypogonadism (IHH) is the most common disorders of sex development (DSD).Therapy for IHH includes hormone replacement therapy, gonadotropin therapy and pulsed infusion of g...
Eligibility Criteria
Inclusion
- Age greater than 16 yr
- Diagnosed as idiopathic hypogonadotropic hypogonadism with clinical signs or symptoms of hypogonadism
- Hypogonadal serum testosterone levels (\<166ng/dl) in the presence of low or normal gonadotropins
- Normal levels of other anterior pituitary hormones
- Normal MRI scans of the hypothalamo-pituitary region
- Had discontinued any prior treatment (testosterone or gonadotropin therapy) for at least three months before enrollment
Exclusion
- With any significant medical condition (including malignant disease), laboratory abnormality, or psychiatric disorders that will prevent the subject from participating in the study
- Congenital hypopituitarism
- Any medical or surgical conditions possibly affecting the experiment result
- Any clinically significant allergic diseases or allergic to the study drugs
- Recently drug or alcohol abuse(\>35unit/week,1unit=8 g alcohol@1 standard drink@250ml beer@140ml wine@25ml strong alcohol drink like whiskey.)
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
76 Patients enrolled
Trial Details
Trial ID
NCT02310074
Start Date
January 1 2010
Last Update
February 3 2015
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.