Status:
COMPLETED
The Efficacy of L-cysteine in Prevention of Cluster Headache
Lead Sponsor:
Biohit Oyj
Collaborating Sponsors:
The Finnish Funding Agency for Technology and Innovation (TEKES)
Conditions:
Cluster Headache
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The purpose of this study is to validate the novel hypothesis that daily use of L-cysteine (Acetium® capsules) is an effective means to decrease the frequency of (or completely abort) the attacks of c...
Detailed Description
Background: Cluster headache belongs to a group of idiopathic headache entities, the trigeminal autonomic cephalalgias (TACs), all of which involve short-lasting, unilateral, severe headache attacks a...
Eligibility Criteria
Inclusion
- 18-65 years male/female
- episodic and chronic cluster headache
- the subjects should report cluster headache attacks with the frequency from one every second day up to five per day. The individual attacks should last from 15 minutes to 3h.
Exclusion
- patients who meet the International Classification of Headache Disorders II criteria for medication overuse
- patients who have taken anti-psychotics or anti-depressant medications during the previous 3 months
- patients who abuse alcohol or other drugs
- potentially fertile and sexually active women who do not practise contraception
- other acute or chronic pain disorders
- severe psychiatric disease
- infections
- malignancy
- short life expectancy
- cardiovascular disease
- cerebrovascular disease
- uncontrolled hypertension
- degenerative central nervous system diseases
- pregnant and lactating women
- regular users of Acetium capsules for other indications
- renal dysfunction or cystinuria
Key Trial Info
Start Date :
December 17 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 14 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02310828
Start Date
December 17 2013
End Date
October 14 2020
Last Update
February 17 2021
Active Locations (6)
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1
Terveystalo, Kamppi
Helsinki, Finland, 00100
2
Lääkärikeskus Aava, Helsingin Päänsärkykeskus Oy
Helsinki, Finland, 00930
3
Terveystalo, Jyväskylä
Jyväskylä, Finland, 40100
4
Terveystalo, Oulu
Oulu, Finland, 90100