Status:

UNKNOWN

Uterine Cavity Assessment and Endometrial Gene Expression in Tamoxifen Treated Breast Cancer Patients

Lead Sponsor:

Sheba Medical Center

Conditions:

Endometrial Receptivity Post Tamoxifen Exposure

Eligibility:

FEMALE

18-45 years

Brief Summary

The aim of this multi-center study is to assess the effects of Tamoxifen on the uterine cavity and endometrial abnormalities in young premenopausal women diagnosed with breast cancer. The research co...

Detailed Description

Breast cancer is the most prevalent malignancy amongst women and approximately 13% of newly diagnosed breast cancer patients are diagnosed between the ages 20-34 \[1\]. At this age group women are at ...

Eligibility Criteria

Inclusion

  • Breast cancer patients who are:
  • \< 45 years
  • premenopausal
  • Had no previous uterine operations (previous D\&C is allowed)
  • Currently receiving or having received Tamoxifen for at least 1 year.

Exclusion

  • None

Key Trial Info

Start Date :

January 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2017

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT02311647

Start Date

January 1 2015

End Date

February 1 2017

Last Update

December 23 2014

Active Locations (1)

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1

The Chaim Sheba Medical Center

Tel Litwinsky, Israel, 52621