Status:
COMPLETED
A Pilot Study of Transcoronary Myocardial Cooling
Lead Sponsor:
Royal Brompton & Harefield NHS Foundation Trust
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Patients with heart attacks caused by blocked coronary arteries are usually treated with a technique called primary angioplasty. Although this treatment is very successful it can result in damage to t...
Detailed Description
The precise mechanisms involved in ischaemia/reperfusion injury is not fully understood but a number of factors are thought to contribute to cardiac dysfunction14, 15. These include : 1. reperfusion a...
Eligibility Criteria
Inclusion
- Men and women aged between 18 and 80 years presenting with ischaemic chest pain of \<6 hours and STsegment elevation on the ECG of \>0.2 mV in 2 contiguous leads.
Exclusion
- Patients with cardiac arrest, previous AMI or CABG, known congestive heart failure, endstage kidney disease or hepatic failure, recent stroke, coagulopathy, pregnancy, or cardiogenic shock.
- Patients who are unable or unwilling to provide assent and informed consent.
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT02312336
Start Date
September 1 2014
End Date
July 1 2015
Last Update
July 28 2015
Active Locations (1)
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1
Royal Brompton and Harefield NHS Foundation Trust
Uxbridge, Middlesex, United Kingdom, UB9 6JH