Status:

UNKNOWN

Effects of Carnitine on Oxidative Stress to IVIR Administration to CKD Patients:Impact of Haptoglobin Genotype

Lead Sponsor:

The Nazareth Hospital, Israel

Conditions:

Anemia

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Anemia is a common disorder in CKD patients. It is largely attributed to decreased erythropoietin (EPO) production and iron deficiency. Therefore, besides EPO, therapy includes iron replenishment. How...

Detailed Description

This study will include at least 25 anemic CKD patients (stages 3-4) that will be given a weekly IVIR (Sodium ferric gluconate, \[125 mg/100 ml\] for 8 weeks, and during weeks 5-8 also received Carnit...

Eligibility Criteria

Inclusion

  • Patients that have been diagnosed as suffering from chronic kidney diseases at stages 3-4 and confirmed by MDRD.
  • CKD patients with Hb of less than 10 g%.
  • At age ≥18 y.

Exclusion

  • Pregnant women.
  • Patient with CKD stage 5 on Dialysis.
  • Patients with severe liver diseases.
  • Patients with severe CHF.
  • Inter-current illness such as fever.
  • Allergic rhinitis.

Key Trial Info

Start Date :

October 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT02312414

Start Date

October 1 2014

Last Update

May 18 2015

Active Locations (1)

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Nazareth hospital (EMMS)

Nazareth, Israel

Effects of Carnitine on Oxidative Stress to IVIR Administration to CKD Patients:Impact of Haptoglobin Genotype | DecenTrialz