Status:

COMPLETED

DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure

Lead Sponsor:

Mitsui Memorial Hospital

Collaborating Sponsors:

Mitsukoshi Health and Welfare Foundation

Conditions:

Heart Failure

Diabetes Mellitus

Eligibility:

All Genders

20+ years

Phase:

PHASE4

Brief Summary

We thought to investigate the influence of DPP-4 inhibitor on the serum BNP level of diabetic patients with congestive heart failure. This study consists of two protocols. In the first protocol, diabe...

Eligibility Criteria

Inclusion

  • Outpatient arm
  • Type 2 diabetes patient with congestive heart failure under treatment with DPP-4 inhibitor (sitagliptin, vildagliptin, alogliptin, linagliptin, teneligliptin, anagliptin or saxagliptin) .
  • High serum BNP (100-2000pg/ml).
  • Patients who have given informed consent to participation in the study.

Exclusion

  • HbA1c over 9.0%.
  • Patients who changed medication within 1 months before inclusion.
  • Judged as ineligible by clinical investigators.
  • Hospitalization arm
  • Inclusion Criteria:
  • Type 2 diabetes patient who were hospitalized for congestive heart failure.
  • Patients who have given informed consent to participation in the study.

Key Trial Info

Start Date :

January 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2016

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT02312427

Start Date

January 1 2015

End Date

March 1 2016

Last Update

March 22 2018

Active Locations (1)

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Mitsui Memorial Hospital

Taito-ku, Tokyo, Japan