Status:

COMPLETED

Treatment of Infertility by Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchyma Stem Cells

Lead Sponsor:

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Collaborating Sponsors:

Institute of genetic development, Chinese Academy of Sciences

Institute of Zoology, Chinese Academy of Sciences

Conditions:

Infertility

Intrauterine Adhesions

Eligibility:

FEMALE

20-45 years

Phase:

NA

Brief Summary

Study of the treatment of infertility caused by recurrent intrauterine adhesions (IUA) by collagen scaffold loaded with umbilical cord derived mesenchymal stem cells (UC-MSCs) to provide clinical evid...

Detailed Description

Infertility is defined as a women fails to become pregnant after having a normal sex life for two years without contraception. There is limited treatment to the infertility caused by severe IUA especi...

Eligibility Criteria

Inclusion

  • Secondary infertility or failure of embryo transfer caused by recurrent intrauterine adhesions who desired to be pregnant
  • Hysteroscopy examination confirmed intrauterine adhesions
  • Sign a consent form
  • Follow the test plan and follow-up process

Exclusion

  • have hysteroscopic contraindications
  • Chromosome karyotype abnormalities
  • Congenital uterine malformations
  • Severe adenomyosis
  • Contraindications to estradiol treatment
  • Medical history of pelvic tumors or receiving pelvic radiotherapy

Key Trial Info

Start Date :

November 28 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2017

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT02313415

Start Date

November 28 2014

End Date

August 31 2017

Last Update

October 24 2017

Active Locations (1)

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Nanjing Drum Tower Hospital

Nanjing, Jiangsu, China, 210008