• INCLUSION CRITERIA:

Participants will be eligible if they:

• Are 12 years of age or older.
• Have the ability to cooperate with an eye exam and adaptive optics imaging.
• Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children.
• Have an eye disease or are a healthy volunteer with a normal eye exam (no visually-significant eye findings on examination).

EXCLUSION CRITERIA:

Participants will not be eligible if:

-They have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity).

EXCLUSION CRITERIA FOR FLUORESCEIN AND/OR INDOCYANINE GREEN IMAGING

Partaicipants are not eligible for fluorescein and/or indocyanine green imaging if they:

• Are under 18 years of age.
• For participants who will undergo fluorescein imaging have a history of adverse reaction to fluorescein.
• For participants who will undergo indocyanine green imaging have a history of adverse reaction to indocyanine green dye, know or suspected allergies to iodine or shellfish.