Status:
COMPLETED
A Longitudinal Follow-up Imaging Study on Children and Adolescents With Autism Spectrum Disorder
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Autism Spectrum Disorder
Eligibility:
All Genders
12-20 years
Brief Summary
The significance of this project is the first longitudinal study to investigate the changes of neurocognitive functions of children and adolescents with ASD and to identify the potential neuroimaging ...
Detailed Description
Autism spectrum disorder (ASD) is a common severe, clinically and genetically heterogeneous childhood-onset neurodevelopmental disorder. Due to its high prevalence, typical autistic symptoms, and seve...
Eligibility Criteria
Inclusion
- ASD group:
- have a clinical diagnosis of autistic disorder or Asperger disorder defined by the DSM-IV and ICD-10 criteria, made by board-certificated child psychiatrists and who were clinically diagnosed with ASD confirmed by the ADI-R 3-5 years ago
- ages range from 12 to 20 (i.e., 7-17 years old at the first assessment)
- both parents are Han Chinese
- have complete clinical and behavioral data at the 1st assessment
- participants and their parents consented to participate in this longitudinal study 3-5 years ago for complete assessments at follow-up.
- TD group:
- ages range from 12 to 20
- both parents are Han Chinese
Exclusion
- comorbidity with DSM-IV-TR or DSM-5 diagnoses of ASD, ADHD, schizophrenia, schizoaffective disorder, delusional disorder, other psychotic disorder, organic psychosis, schizotypal personality disorder, bipolar disorder, depression, severe anxiety disorders or substance use
- comorbidity with neurological or systemic disorders
- having a first degree relative who may have ASD based on family history method assessment.
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2016
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT02719067
Start Date
January 1 2016
End Date
December 31 2016
Last Update
September 2 2021
Active Locations (1)
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1
National Taiwan Univeristy Hospital
Taipei, Taiwan