Status:
COMPLETED
Southend Imaging Study
Lead Sponsor:
Mid and South Essex NHS Foundation Trust
Collaborating Sponsors:
Anglia Ruskin University
Conditions:
Cognition Disorders
Eligibility:
All Genders
18-100 years
Brief Summary
The study objective is to correlate global cognition and episodic memory performance to resting state fMRI functional connectivity. This is a non-treatment, prospective, natural history data collectio...
Detailed Description
At present, Magnetic Resonance Imaging (MRI) is widely used along with other tests to help diagnose dementia, however diagnosis still remains challenging. There is currently a focus on the usefulness ...
Eligibility Criteria
Inclusion
- Informed consent
- Cognitive impairment
- Age from 18 to 100 years
- On stable medication for 1 month before the screening visit; on or off cholinesterase inhibitors
- Fluency in English and adequate premorbid intellectual functioning
Exclusion
- Any contraindication to MRI scanning
- Clinically significant psychiatric disorder (e.g. depression)
- Current clinically significant illness that could confound the results of the study
- History of alcohol or drug dependence or abuse
- Current use of anticonvulsant or narcotic medications.
Key Trial Info
Start Date :
June 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2020
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT02736396
Start Date
June 1 2016
End Date
September 1 2020
Last Update
December 22 2020
Active Locations (1)
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1
Southend Hospital
Westcliff-on-Sea, Essex, United Kingdom, SS0 0RY