Status:
RECRUITING
Clinical and Molecular Studies in Families With Inherited Eye Disease
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Inherited Eye Disease
Eligibility:
All Genders
4-120 years
Brief Summary
Background: Genes are the basic units of heredity. When genes are changed, certain cells don t work like they should. Researchers want to try to better understand the genetic conditions that are link...
Detailed Description
Objective: This project, Clinical and Molecular Studies in Families with Inherited Eye Disease will study inherited eye diseases, both Mendelian and complex age related inherited eye diseases, in fami...
Eligibility Criteria
- INCLUSION CRITERIA:
To be eligible, the following inclusion criteria must be met, where applicable;
- Participant must be four years of age or older.
- Participant must understand and sign the protocol s informed consent document.
- Individuals or family members of individuals with inherited eye diseases, either congenital, childhood, or age related.
- All participants must be able to cooperate with study examination and phlebotomy.
EXCLUSION CRITERIA:
A participant is not eligible if any of the following exclusion criteria are present:
- Participant has a disease, infection, or trauma that mimics inherited cataracts, retinal degenerations, glaucoma, etc.
- Participant has a significant active infection (an infection requiring treatment as determined by the investigator) or a history of chronic or recurrent infections.
- Participant requires sedation for study purposes.
Key Trial Info
Start Date :
October 4 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2032
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT02771236
Start Date
October 4 2016
End Date
January 1 2032
Last Update
April 14 2026
Active Locations (10)
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1
University of California, San Diego
La Jolla, California, United States, 92093-0603
2
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
3
Duke University Eye Center
Durham, North Carolina, United States, 27708
4
Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat Sen University
Guangzhou, China