Status:

RECRUITING

Clinical and Molecular Studies in Families With Inherited Eye Disease

Lead Sponsor:

National Eye Institute (NEI)

Conditions:

Inherited Eye Disease

Eligibility:

All Genders

4-120 years

Brief Summary

Background: Genes are the basic units of heredity. When genes are changed, certain cells don t work like they should. Researchers want to try to better understand the genetic conditions that are link...

Detailed Description

Objective: This project, Clinical and Molecular Studies in Families with Inherited Eye Disease will study inherited eye diseases, both Mendelian and complex age related inherited eye diseases, in fami...

Eligibility Criteria

  • INCLUSION CRITERIA:

To be eligible, the following inclusion criteria must be met, where applicable;

  1. Participant must be four years of age or older.
  2. Participant must understand and sign the protocol s informed consent document.
  3. Individuals or family members of individuals with inherited eye diseases, either congenital, childhood, or age related.
  4. All participants must be able to cooperate with study examination and phlebotomy.

EXCLUSION CRITERIA:

A participant is not eligible if any of the following exclusion criteria are present:

  1. Participant has a disease, infection, or trauma that mimics inherited cataracts, retinal degenerations, glaucoma, etc.
  2. Participant has a significant active infection (an infection requiring treatment as determined by the investigator) or a history of chronic or recurrent infections.
  3. Participant requires sedation for study purposes.

Key Trial Info

Start Date :

October 4 2016

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2032

Estimated Enrollment :

5000 Patients enrolled

Trial Details

Trial ID

NCT02771236

Start Date

October 4 2016

End Date

January 1 2032

Last Update

April 14 2026

Active Locations (10)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 3 (10 locations)

1

University of California, San Diego

La Jolla, California, United States, 92093-0603

2

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

3

Duke University Eye Center

Durham, North Carolina, United States, 27708

4

Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat Sen University

Guangzhou, China