Status:

COMPLETED

Type 2 Diabetes and Alteration of Immune System of Intestinal Mucosa : Proof of Concept

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Type 2 Diabetes

Eligibility:

All Genders

35-70 years

Brief Summary

Type 2 diabetes is the predominant type of diabetes. Because a quiet evolution, it is difficult to have a rapid diagnose. A better knowledge about pathophysiological mechanisms at the origin of type 2...

Eligibility Criteria

Inclusion

  • Coloscopy indication
  • Capacity to give a written informed consent

Exclusion

  • Type 1 diabetes
  • Severe renal failure
  • Antecedent of liver fibrosis and/or liver failure
  • Antecedent of inflammatory bowel disease, lymphocyte colitis, celiac disease or colon cancer
  • Antecedent of obesity surgery or of total colectomy
  • Antecedent of documented intestinal ischaemia
  • Acute infection the week before the inclusion
  • Congenital of acquired immune deficiency
  • Chronic viral infection
  • Antibiotic of probiotic the month before the coloscopy
  • Pregnancy
  • Patients participating to another research with an exclusion period
  • Patients under guardianship

Key Trial Info

Start Date :

December 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 4 2021

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT02811575

Start Date

December 1 2016

End Date

March 4 2021

Last Update

February 7 2022

Active Locations (1)

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1

CHU de Toulouse

Toulouse, France, 31059