Status:
COMPLETED
The Utility of Circulating Tumour Cells and Plasma microRNA in Esophageal Adenocarcinoma
Lead Sponsor:
University Health Network, Toronto
Conditions:
Esophageal Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Circulating microRNA (circ miRNA) and circulating tumor cell (CTC) levels are hypothesized to be associated with response to chemoradiation in patients undergoing treatment for locally advanced esopha...
Detailed Description
Recently, different groups have discovered that miRNAs can be detected in body fluids such as plasma, serum or saliva. These cell-free miRNAs are secreted by cells under different forms. Levels of the...
Eligibility Criteria
Inclusion
- Patients who are at least 18 years of age
- Patients with Esophageal Adenocarcinoma who will undergo neo-adjuvant therapy with surgical resection.
- Patients with esophageal adenocarcinoma who will be treated with chemotherapy, chemotherapy and radiation or radiation alone OR
- Healthy volunteers who are at least 18 years of age
Exclusion
- Patients who are treated with surgery alone for esophageal cancer
- Patients who have a history of invasive cancer
Key Trial Info
Start Date :
June 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2020
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT02812680
Start Date
June 1 2016
End Date
November 1 2020
Last Update
March 8 2024
Active Locations (1)
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1
University Health Network
Toronto, Ontario, Canada, M5G 2C4