Status:

COMPLETED

An Optical Neuro-monitor of Cerebral Oxygen Metabolism and Blood Flow for Neonatology

Lead Sponsor:

Gorm Greisen

Conditions:

Hemodynamic Instability

Eligibility:

All Genders

Up to 4 years

Brief Summary

Feasibility trial on the use of a hybrid optical device integrating time-resolved near-infrared spectroscopy (TRS) and diffuse correlation spectroscopy (DCS) for measurement of cerebral oxygen metabol...

Detailed Description

The BabyLux project aims to provide a precise, accurate, and robust device to continuously monitor cerebral oxygen metabolism and blood flow in critically ill newborn infants. This will be achieved by...

Eligibility Criteria

Inclusion

  • Setting 1 and 2:
  • GA \> 37 weeks
  • planned to be delivered by an uncomplicated elective caesarean section

Exclusion

  • need for resuscitation or supplementary oxygen during the first 10 minutes following umbilical cord clamping
  • congenital malformations
  • Setting 3:
  • Inclusion Criteria:
  • GA \< 37 weeks
  • Postnatal age more \> 24 hours
  • Mechanically ventilated
  • Clinically stable
  • Normal brain ultrasound
  • Transcutaneous pCO2 monitoring (tcpCO2)

Key Trial Info

Start Date :

June 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2022

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT02815618

Start Date

June 1 2016

End Date

December 1 2022

Last Update

March 28 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Rigshospitalet

Copenhagen, Denmark, 2100

2

IRCCS Ca'Granda Ospedale Maggiore Policlinico

Milan, Italy, 20122