Status:
COMPLETED
Exercise and Ectopic Fat Deposition
Lead Sponsor:
Universiteit Antwerpen
Conditions:
Overweight
Eligibility:
FEMALE
18-60 years
Phase:
NA
Brief Summary
Excess ectopic fat deposition is associated with development of cardiovascular and metabolic diseases. This study investigates how lifestyle interventions can have an effect on different sites of ecto...
Detailed Description
protocol of the study was published, Hens et al. (physioscience 2017; 13: 80-87)
Eligibility Criteria
Inclusion
- Participants should be willing to undergo a weight loss intervention and body weight must be stable during the past six months.
- There will be no upper eligibility criterion for body mass index (BMI) but BMI should be at least 27 kg/m².
Exclusion
- Individuals who have a clinical history of type 2 diabetes, prediabetes (with use of medication), or hypothyroidism will be excluded.
- when postmenopausal; Premenopausal state will be verified by hormonal data (follicle-stimulation hormone (FSH) \< 25 mU/ml and estradiol \> 20 pg/ml).
- Subjects will not be allowed when pregnancy is planned
- when physical activity is not possible due to problems of the musculoskeletal system
- when changes in medication (e.g. beta blockers) are advised by an endocrinologist.
- when smoking
- when drinking more than two alcoholic consumptions/day or binge drinking (self-reported)
- when taking medication that influences body weight or metabolism (e.g. tricyclic antidepressants)
- Since all participants will undergo medical imaging, exclusion criteria related to MRI and CT scans are also applicable.
Key Trial Info
Start Date :
June 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02831621
Start Date
June 1 2016
End Date
January 1 2019
Last Update
January 25 2019
Active Locations (1)
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1
University Hospital of Antwerp
Antwerp, Belgium