Status:
COMPLETED
Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.
Lead Sponsor:
Meenakshi Ammal Dental College and Hospital
Conditions:
Periodontal Disease
Periodontal Bone Loss
Eligibility:
All Genders
25-35 years
Phase:
NA
Brief Summary
The present study is an effort to investigate the hypothesis that Platelet Rich Fibrin/Biphasic Calcium Phosphate may play a role in inhibiting osteoclasts differentiation and in bone loss.
Detailed Description
Study design Fifty-five individuals from a suburban population were recruited. Out of them, 5 individuals refused to participate in the study. Finally, 50 participants were selected and divided into ...
Eligibility Criteria
Inclusion
- Inclusion criteria: (Control group)
- Subjects with age group between 30 to 45 years.
- Non-smokers.
- No previous history of periodontal treatment.
- (Test group)
- Subjects with age group between 30 to 45 years.
- Presence of atleast 20 teeth
- More than 30% of the sites with clinical attachment loss.
- Non-smokers.
- No previous history of periodontal treatment.
Exclusion
- ( both the groups)
- Individuals with systemic disease
- Subjects under antibiotics or anti-inflammatory drugs within the previous 3 months.
- Pregnant and lactating women.
- Allergic to antibiotics.
Key Trial Info
Start Date :
March 17 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 18 2017
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03227367
Start Date
March 17 2014
End Date
March 18 2017
Last Update
July 26 2017
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