Status:
COMPLETED
The Effect of Probiotics on Chronic Kidney Disease
Lead Sponsor:
China Medical University Hospital
Conditions:
Chronic Kidney Disease
Probiotics
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Probiotics could attenuate renal function deterioration in CKD patients.
Detailed Description
Chronic kidney disease (CKD) is a global health issue that has a substantial impact on affected individuals. Chronic inflammation, which is widely seen in CKD including long-term dialysis patients, is...
Eligibility Criteria
Inclusion
- Healthy volunteers:
- The criteria for healthy volunteers were: no hypertension (Blood pressure\<140/90mmHg), no diabetes (Glucose AC 70\~100mg/dl), no hyperlipidemia (Cholesterol Total 130\~200mg/dL、Triglyceride\<150mg/dL), no urinary protein (-) and normal renal function (eGFR\>90), after signing the consent form, the stool samples will be collected.
- CKD patients:
- ‧Stage 3-5 CKD patients, at least 20 years of age and regular follow-up for at least 6 months prior to enrollment.
Exclusion
- Pregnancy.
- On immunosuppressive therapy.
- Active infectious condition.
- Acute kidney injury.
- Consuming other forms of probiotics.
- Taking antibiotics within 30 days prior to enrollment.
Key Trial Info
Start Date :
May 23 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2022
Estimated Enrollment :
148 Patients enrolled
Trial Details
Trial ID
NCT03228563
Start Date
May 23 2017
End Date
April 30 2022
Last Update
July 21 2022
Active Locations (1)
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1
China Medical University Hospital
Taichung, Taiwan, 413