Status:
COMPLETED
Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
Lead Sponsor:
The University of Texas Health Science Center, Houston
Conditions:
Endoscopic Sinus Surgery
Nasal Polyps
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the effects of Oxymetazoline and Epinephrine (which are 2 different nasal decongestants both of which are routinely used before sinus surgery) on blood loss and...
Eligibility Criteria
Inclusion
- The inclusion criteria will be patients undergoing bilateral endoscopic sinus surgery (ESS) in which the same sinuses and procedures on both sides are the same for CRS with or without nasal polyposis.
Exclusion
- pregnancy
- known coagulopathy
- an international normalized ratio greater than 1.3
- a partial thromboplastin time greater than 50 seconds
- use of non-steroidal anti-inflammatory drugs in the last 10 days (2 or more doses)
- use of any antiplatelet agents (eg, warfarin, clopidogrel, berlinta)
- poorly controlled hypertension with a preoperative systolic blood pressure of 160mm Hg or greater or a diastolic blood pressure of 90mm Hg or greater
- having any adverse reaction to topical epinephrine or oxymetazoline.
Key Trial Info
Start Date :
June 14 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 29 2018
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03228914
Start Date
June 14 2018
End Date
August 29 2018
Last Update
January 13 2021
Active Locations (1)
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1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030