Status:

COMPLETED

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis

Lead Sponsor:

Spyryx Biosciences, Inc.

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

18-50 years

Phase:

PHASE2

Brief Summary

28-Day double-blinded efficacy and safety trial of SPX-101 Inhalation Solution in adult subjects with cystic fibrosis.

Eligibility Criteria

Inclusion

  • Confirmed diagnosis of cystic fibrosis
  • ppFEV1 (percent predicted FEV1) between 50.0% and 80.0%
  • Stable CF Lung Disease
  • Males and non-pregnant, non-lactating females

Exclusion

  • Significant unstable co-morbidities within 28 days of screening
  • Has received an investigational drug within 28 days of screening

Key Trial Info

Start Date :

August 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 20 2019

Estimated Enrollment :

91 Patients enrolled

Trial Details

Trial ID

NCT03229252

Start Date

August 1 2017

End Date

June 20 2019

Last Update

December 30 2019

Active Locations (25)

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Page 1 of 7 (25 locations)

1

University of Calgary Heritage Medical Research Center

Calgary, Alberta, Canada, T2N 1N4

2

Ottawa Hospital Research Institute/Institut de Recherche de l'Hospital d'Ottawa

Ottawa, Ontario, Canada, K1H 8L6

3

Saint Michael's Hospital

Toronto, Ontario, Canada, M5B1W8

4

Hospices Civils de Lyon (HCL)

Pierre-Bénite, Auvergne-Rhône-Alpes, France