Status:
COMPLETED
Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium Anesthesia
Lead Sponsor:
Pusan National University Yangsan Hospital
Conditions:
Emergence Delirium
Eligibility:
All Genders
2-7 years
Phase:
PHASE4
Brief Summary
The aim of this study is to investigate the effect of sugammadex vs. a conventional acetylcholinesterase inhibitor, neostigmine on emergence delirium (ED) during sevoflurane-rocuronium anesthesia in p...
Detailed Description
Emergence delirium (ED) is a postanesthetic phenomenon that develops in the early phase of general anesthesia recovery, (usually within the first 30 minutes,) and is defined as "a disturbance in a chi...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologist (ASA) physical status I or II, preschool children scheduled for an elective tonsillectomy with or without adenoidectomy will be included in the study.
Exclusion
- Patients will be excluded in cases of emergency surgery, developmental, psychological, cognitive or communication disorders, known or suspected neuromuscular disorders that may impair neuromuscular blockade, significant renal or hepatic dysfunction, coagulation disorders, family history of malignant hyperthermia, allergy to any of the drugs included in the study protocol, or usage of medication known to interact with rocuronium or sugammadex.
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2019
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03229486
Start Date
March 1 2017
End Date
December 30 2019
Last Update
March 17 2020
Active Locations (1)
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1
Pusan National University Yangsan Hospital
Yangsan, Gyeongsangnam-do, South Korea, 50612